Generic Name and Formulations:
Dyphylline 200mg, 400mg; scored tabs.
For relief of acute bronchial asthma and for reversible bronchospasm associated with chronic bronchitis and emphysema.
Individualize. Usual dose: up to 15mg/kg every 6 hours. Renal impairment: adjust dose.
Not for primary treatment of acute attack. Severe cardiac disease. Hypertension. Hyperthyroidism. Acute myocardial injury. Peptic ulcer. Pregnancy (Cat.C). Nursing mothers.
Toxicity with concomitant sympathomimetics. Potentiated by probenecid.
GI upset, epigastric pain, hematemesis, headache, irritability, restlessness, insomnia, hyperexcitability, agitation, muscle twitching, generalized clonic and tonic convulsions, palpitation, tachycardia, extrasystoles, flushing, hypotension, circulatory failure, ventricular arrhythmias, tachypnea, gross and microscopic hematuria, diuresis, hyperglycemia, inappropriate ADH syndrome.
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