Generic Name and Formulations:
Various generic manufacturers
Treatment of scabies in patients who have failed on, or are intolerant of, other therapies. Not for prophylactic use.
Treat once only. Use least amount to cover body. <110lbs: not recommended. ≥110lbs: average size adult: 30mL; larger adult: max 60mL. Apply sparingly to dry skin; leave on for 8–12 hours then wash off thoroughly.
Uncontrolled seizure disorders. Premature infants. Norwegian (crusted) scabies, other skin conditions (eg, eczema, psoriasis, broken skin) that may increase absorption.
Potential CNS toxicity if absorbed. Children, infants, elderly, patients <110lbs: increased neurotoxicity risk. Seizure risk (eg, history of head trauma, prior seizures, CNS tumor, HIV infection, hepatic cirrhosis, abrupt alcohol/sedative withdrawal). Itching may occur or worsen after successful treatment; do not retreat. Avoid eyes. Do not swallow or misuse. Pregnancy (Cat.C), nursing mothers: not recommended.
Systemic absorption and toxicity may be increased by oils, creams, ointments. Caution with drugs that lower seizure threshold (eg, antipsychotics, antidepressants, quinolones, theophylline, cyclosporine).
Irritation, post-treatment pruritus, CNS stimulation (eg, dizziness, convulsions).
Formerly known under the brand names Gamene, Kwell, Scabene.
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