Generic Name and Formulations:
Aminolevulinic acid HCl 20%; topical soln; contains alcohol.
DUSA Pharmaceuticals, Inc.
In combination with blue light illumination (BLU-U Blue Light Photodynamic Therapy Illuminator), for the treatment of minimally to moderately thick actinic keratoses (Grade 1 or 2) of the face and scalp.
Clean and dry affected area. Apply to either scalp or face but not both simultaneously. One application and one dose of illumination per treatment site per 8-week treatment session. The second visit, for illumination, must take place in the 14–18 hour window following application. Treated lesions not completely resolved after 8 weeks may be treated a second time. Protect treated lesions from sun by wearing head covering. Excessive irritation if applied under occlusion.
Cutaneous photosensitivity at wavelengths of 400–450nm. Porphyria or known allergies to porphyrins.
Avoid exposure of photosensitive treatment sites to sunlight or bright indoor light during the period prior to blue light treatment. Avoid applying to eyes, mucous membranes, perilesional skin. Inherited or acquired coagulation defects. Pregnancy (Cat.C). Nursing mothers.
Increased photosensitivity reaction with concomitant photosensitizing agents (eg, griseofulvin, thiazides, sulfonylureas, phenothiazines, sulfonamides, tetracyclines).
Cutaneous reactions (eg, stinging, burning, erythema, edema, scaling/crusting, itching, erosion, wheal/flare).
Single-unit applicators—1, 6
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