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Drug Name:


Generic Name and Formulations:
Penbutolol sulfate 20mg; scored tabs.

Auxilium Pharmaceuticals, Inc.

Therapeutic Use:

Indications for LEVATOL:



20mg once daily.


Not recommended.


Asthma. Cardiogenic shock. Sinus bradycardia. 2nd- or 3rd-degree AV block.


Overt heart failure. CHF. Bronchospasm, COPD. Diabetes. Hyperthyroidism. Surgery. Avoid abrupt cessation. Pregnancy (Cat.C). Nursing mothers.


Bradycardia with catecholamine-depleting drugs. May increase cardiac effects of calcium channel blockers, digitalis. Adjust antidiabetic medication. Higher lidocaine loading dose may be needed. May block epinephrine.

Pharmacological Class:

Noncardioselective beta-blocker.

Adverse Reactions:

Bradycardia, headache, dizziness, fatigue, GI upset, cough, dyspnea, insomnia, asthenia, hyperhidrosis, impotence, cardiac failure.

How Supplied:


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