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Hereditary angioedema
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Drug Name:


Generic Name and Formulations:
Ecallantide 10mg/mL; soln for SC inj; preservative-free.

Shire US, Inc.

Therapeutic Use:

Indications for KALBITOR:

Treatment of acute attacks of hereditary angioedema (HAE).


Give 30mg SC in three 10mg (1mL) inj into abdomen, thigh, or upper arm. May give additional 30mg within 24hrs if attack persists.


<12yrs: not established.


Have medical support available to manage anaphylaxis and hereditary angioedema. Monitor closely for hypersensitivity reactions. Labor & delivery. Pregnancy (Cat.C). Nursing mothers.

Pharmacological Class:

Plasma kallikrein inhibitor.

Adverse Reactions:

Headache, nausea, diarrhea, pyrexia, inj site reactions, nasopharyngitis, fatigue, upper respiratory tract infection, pruritus, upper abdominal pain; anaphylaxis, antibody formation.

Generic Availability:


How Supplied:

Single-use vials—3

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