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Hydralazine Tablets
Hypertension
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Drug Name:

Hydralazine Tablets Rx

Generic Name and Formulations:
Hydralazine HCl 10mg, 25mg, 50mg, 100mg.

Company:
Various generic manufacturers

Therapeutic Use:

Indications for Hydralazine Tablets:

Hypertension.

Adult:

Initially 10mg 4 times daily for 2–4 days, then increase to 25mg 4 times daily for rest of 1st week, then to 50mg 4 times daily; max 300mg/day.

Children:

Initially 0.75mg/kg per day in 4 divided doses, increase gradually over 3–4 weeks; max 7.5mg/kg or 200mg daily.

Contraindications:

Coronary artery disease. Mitral valve disease.

Warnings/Precautions:

Suspected coronary artery disease. Cerebrovascular accidents. Aortic aneurysm. Increased intracranial pressure. Renal disease. Treat paresthesias and/or numbness with pyridoxine. Discontinue if blood dyscrasias occur. Obtain CBC and ANA titer periodically; consider discontinuing if SLE occurs. Surgery. Pregnancy (Cat.C). Nursing mothers.

Interactions:

Caution with MAOIs. Profound hypotension with potent parenteral antihypertensives (eg, diazoxide). Antagonized by NSAIDs. May block epinephrine.

See Also:

Hydralazine Injection

Pharmacological Class:

Vasodilator.

Adverse Reactions:

Headache, anorexia, GI disturbances, palpitations, edema, flushing, nasal congestion, lacrimation, rash, tachycardia, angina, orthostatic hypotension, blood dyscrasias, peripheral neuritis, SLE.

Note:

Formerly known under the brand names Apresoline (inj, tabs); Dralzine (tabs).

How Supplied:

Contact supplier.

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