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GELSYN-3
Arthritis/rheumatic disorders
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Drug Name:

GELSYN-3 Rx

Generic Name and Formulations:
Sodium hyaluronate 0.84%; per 2mL; soln for intra-articular inj.

Company:
Bioventus

Therapeutic Use:

Indications for GELSYN-3:

Treatment of pain in osteoarthritis of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy and simple analgesics (eg, acetaminophen).

Adult:

Remove synovial fluid or effusion before inj. Give as a single intra-articular inj. >21yrs: 2mL in one knee only once weekly for 3 weeks.

Children:

≤21yrs: not established.

Contraindications:

Knee joint infections. Skin diseases or infections in area of the inj site.

Warnings/Precautions:

Do not inject by intravascular route. Severe intra-articular effusion. Lymphatic or venous stasis in leg. Advise patients to avoid strenuous or prolonged weight-bearing activities for approx. 48hrs following inj. Pregnancy, nursing mothers: not established.

Interactions:

Avoid use of disinfectants containing quaternary ammonium salts; hyaluronan can precipitate in their presence. Concomitant other intra-articular inj: not studied.

Pharmacological Class:

Hyaluronan.

Adverse Reactions:

Inj site pain, arthralgia, joint effusion/warmth/stiffness/swelling, arthritis, gait disturbance, arthropathy.

Generic Availability:

NO

How Supplied:

Single-use pre-filled syringe—1 (w. needle)

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