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Drug Name:


Generic Name and Formulations:
Pentosan polysulfate sodium 100mg; caps.

Janssen Pharmaceuticals, Inc.

Therapeutic Use:

Indications for ELMIRON:

Bladder pain/discomfort due to interstitial cystitis.


Take with water 1 hr before or 2 hrs after meals. ≥16yrs: 100mg 3 times daily. Reevaluate at 3 and 6 months.


<16yrs: not recommended.


Bleeding or risk of bleeding (eg, surgery, aneurysm, GI ulcer, polyps). History of heparin-induced thrombocytopenia. Hepatic insufficiency. Splenic disorders. Pregnancy (Cat.B). Nursing mothers.


Caution with drugs that increase bleeding risk (eg, anticoagulants, tPA, aspirin, NSAIDs).

Pharmacological Class:

Bladder protectant.

Adverse Reactions:

Alopecia, GI upset, headache, rash, abdominal pain, hepatic dysfunction, dizziness, increased prothrombin time, hemorrhage.

How Supplied:


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