Generic Name and Formulations:
Pentosan polysulfate sodium 100mg; caps.
Janssen Pharmaceuticals, Inc.
Bladder pain/discomfort due to interstitial cystitis.
Take with water 1 hr before or 2 hrs after meals. ≥16yrs: 100mg 3 times daily. Reevaluate at 3 and 6 months.
<16yrs: not recommended.
Bleeding or risk of bleeding (eg, surgery, aneurysm, GI ulcer, polyps). History of heparin-induced thrombocytopenia. Hepatic insufficiency. Splenic disorders. Pregnancy (Cat.B). Nursing mothers.
Caution with drugs that increase bleeding risk (eg, anticoagulants, tPA, aspirin, NSAIDs).
Alopecia, GI upset, headache, rash, abdominal pain, hepatic dysfunction, dizziness, increased prothrombin time, hemorrhage.
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