This site is intended for healthcare professionals


Select the drug indication to add to your list

Compare To Related Drugs
View/Edit/Compare Drugs In My List

Only 4 drugs may be compared at once

Drug Name:


Generic Name and Formulations:
Cyanocobalamin 1000mcg, salcaprozate sodium 100mg; tabs.

Emisphere Technologies

Therapeutic Use:

Indications for ELIGEN B12:

Dietary management of patients with Vit. B12 deficiency that cannot be managed by a modification of the normal diet alone (eg, pernicious anemia, malabsorption of Vit. B12, others).


Take on empty stomach (at least 1hr before a meal) with water. ≥18yrs: initially 1 tab daily; may adjust up to max 2 tabs daily.


<18yrs: not established.


Sensitivity to cobalt. Hereditary optic nerve atrophy (Leber's disease).


Confirm diagnosis. Risk of hypokalemia and sudden death in severe megaloblastic anemia. Infection, uremia, and iron or folic acid deficiency may reduce response. May unmask polycythemia vera. Obtain hematocrit, reticulocyte count, Vit. B12, folate, iron levels prior to treatment. May need supplemental folate. Reevaluate if low levels of Vit. B12 persist despite treatment. Monitor B12 blood levels 1 month after starting therapy, 1 month after any dose increase, and regularly at 3–6 month intervals. Monitor serum potassium, platelet counts. Pregnancy.


Antibiotics, methotrexate, pyrimethamine may interfere with lab tests. Colchicine, para-aminosalicylic acid, chronic heavy alcohol use may impair Vit. B12 absorption; may need to adjust dose. Reduced response with bone marrow suppressants (eg, chloramphenicol).

Pharmacological Class:

Medical food.

Adverse Reactions:

Pulmonary edema, CHF, peripheral vascular thrombosis, polycythemia vera, mild transient diarrhea, itching, transitory exanthema, body swelling, possible anaphylactic shock and death.

How Supplied:


Join MIMS Learning now to manage all your CPD and notes in one place!

By registering you agree with our Terms and Conditions and Privacy Policy.

Already a MIMS Learning member?

Sign In Now »
Red flag CPD modules
0.50 Credits
Red flags

Groin swelling - red flag symptomsExternal web site

This red flags article explains signs and symptoms of potentially serious pathology in patients presenting...

0.50 Credits
Red flags

Erectile dysfunction - red flag symptomsExternal web site

This article by Dr Tillmann Jacobi covers the possible red flag symptoms to consider when a patient...

0.50 Credits
Red flags

Headache - red flag symptomsExternal web site

Dr Suneeta Kochhar provides an overview of red flag symptoms in patients presenting with headaches...

Font Awesome Icons
View more
Clinical review CPD modules
1.50 Credits
Clinical Review

Basal cell carcinoma: clinical reviewExternal web site

In this article, Dr David Brass and Dr Neil Rajan discuss the risk factors for BCC, making the diagnosis...

1.50 Credits
Clinical Review

Cardiomyopathy: clinical reviewExternal web site

This article by Dr Rajiv Sankaranarayanan covers the diagnosis and management of cardiomyopathy. Key...

1.50 Credits
Clinical Review

Parkinson's disease: clinical reviewExternal web site

Dr Benjamin Simpson provides an in-depth overview of Parkinson’s disease, including information on risk...

Font Awesome Icons
View more

is free, fast, and customized just for you!

Already a member?

Sign In Now »