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DYNACIN
Acne
Bacterial infections
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Drug Name:

DYNACIN Rx

Generic Name and Formulations:
Minocycline (as HCl) 50mg, 75mg, 100mg; tabs.

Company:
Medicis Pharmaceuticals Corp

Therapeutic Use:

Indications for DYNACIN:

Adjunct in severe acne.

Adult:

Take on empty stomach with fluids. 200mg once then 100mg every 12 hours; or 100–200mg once then 50mg four times daily.

Children:

Take on empty stomach with fluids. <8 years: not recommended. >8 years: 4mg/kg once then 2mg/kg (max 100mg) every 12 hours.

Warnings/Precautions:

Renal or hepatic impairment. Monitor blood, renal and hepatic function in long-term use. Pregnancy (Cat.D), nursing mothers: not recommended.

Interactions:

Antacids, iron, calcium, magnesium, urinary alkalinizers reduce absorption. Avoid penicillins, methoxyflurane. Monitor PT with anticoagulants. May antagonize oral contraceptives.

Pharmacological Class:

Tetracycline antibiotic.

Adverse Reactions:

Dizziness, GI upset, rash, pseudotumor cerebri, blood dyscrasias, increased BUN, interstitial nephritis, hepatotoxicity, tinnitus, tooth discoloration; rare: photosensitivity.

How Supplied:

Tabs 50mg, 75mg—100, 1000
100mg—50, 1000

Indications for DYNACIN:

Susceptible respiratory, genitourinary, skin and soft tissue, ear/nose/throat infections.

Adult:

Take on empty stomach with fluids. 200mg once then 100mg every 12 hours; or 100–200mg once then 50mg four times daily. Syphilis: treat for 10–15 days. Meningococcal carrier state: 100mg every 12 hours for 5 days. Mycobacterium marinum infection: 100mg every 12 hours for 6–8 weeks has been used. Uncomplicated urethral, endocervical, or rectal infection w. C.trachomatis or U. urealyticum: 100mg every 12 hours for at least 7 days. For men: Uncomplicated gonococcal infection (not urethritis or anorectal): 200mg once then 100mg every 12 hours for at least 4 days; urethritis: 100mg every 12 hours for 5 days.

Children:

Take on empty stomach with fluids. <8 years: not recommended. >8 years: 4mg/kg once then 2mg/kg (max 100mg) every 12 hours.

Warnings/Precautions:

Renal or hepatic impairment. Monitor blood, renal and hepatic function in long-term use. Pregnancy (Cat.D), nursing mothers: not recommended.

Interactions:

Antacids, iron, calcium, magnesium, urinary alkalinizers reduce absorption. Avoid penicillins, methoxyflurane. Monitor PT with anticoagulants. May antagonize oral contraceptives.

Pharmacological Class:

Tetracycline antibiotic.

Adverse Reactions:

Dizziness, GI upset, rash, pseudotumor cerebri, blood dyscrasias, increased BUN, interstitial nephritis, hepatotoxicity, tinnitus, tooth discoloration; rare: photosensitivity.

How Supplied:

Tabs 50mg, 75mg—100, 1000
100mg—50, 1000

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