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DORAL
Sleep-wake disorders
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Drug Name:

DORAL CIV

Generic Name and Formulations:
Quazepam 15mg; scored tabs.

Company:
Cutis Health, LLC

Therapeutic Use:

Indications for DORAL:

Insomnia.

Adult:

Use lowest effective dose. ≥18yrs: Initially 7.5mg at bedtime; may increase to 15mg if needed.

Children:

<18yrs: not established.

Contraindications:

Sleep apnea. Pulmonary insufficiency.

Warnings/Precautions:

Risks from concomitant use with opioids; see Interactions. Monitor for CNS depressant effects and daytime impairment. Evaluate for co-morbid diagnoses before initiation (eg, psychiatric or physical disorder). Reevaluate if insomnia persists after 7–10 days of use. Depression. Avoid prolonged use. Drug or alcohol abuse. Write ℞ for smallest practical amount. Avoid abrupt cessation. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers.

Interactions:

Increased sedation, respiratory depression, coma, and death with concomitant opioids; reserve use in those for whom alternative treatment options are inadequate; if needed, limit dosages/durations to minimum and monitor. Concomitant other sedative/hypnotics: not recommended. Additive CNS depressant effects with alcohol or other CNS depressants (eg, other benzodiazepines, TCAs, psychotropics, anticonvulsants, antihistamines); consider dose reductions.

Pharmacological Class:

Benzodiazepine.

Adverse Reactions:

Drowsiness, headache, fatigue, dizziness, dry mouth, dyspepsia; CNS depression, abnormal thinking/behavior changes, complex sleep-related behaviors (eg, sleep-driving), paradoxical reactions, angioedema, anaphylaxis.

How Supplied:

Tabs—100

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