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Drug Name:

Dicloxacillin Rx

Generic Name and Formulations:
Dicloxacillin sodium 250mg, 500mg; caps.

Various generic manufacturers

Therapeutic Use:

Indications for Dicloxacillin :

Susceptible infections caused by penicillinase-producing staphylococci. Not for initial therapy in serious, life-threatening infections.


Take on an empty stomach. ≥40kg: Mild to moderate infections: 125mg every 6hrs. Severe infections: 250mg every 6hrs.


Take on an empty stomach. <40kg: Mild to moderate infections: 12.5mg/kg/day in divided doses every 6hrs. Severe: 25mg/kg/day in divided doses every 6hrs.


Signficant allergy/asthma. Monitor blood, renal, and hepatic function in long-term use. Labor & delivery. Pregnancy (Cat.B). Nursing mothers.


Avoid concomitant tetracyclines, aminoglycosides. Serum levels increased by probenecid. May reduce anticoagulant response: monitor PT.

Pharmacological Class:

Penicillinase-resistant penicillin.

Adverse Reactions:

GI upset, hypersensitivity reactions, neurotoxic reactions, blood dyscrasias; C. difficile associated diarrhea.

How Supplied:

Contact supplier.

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