Generic Name and Formulations:
Acetazolamide 500mg; sust rel caps.
Adjunct in open-angle glaucoma.
500mg twice daily.
Hypokalemia. Hyponatremia. Severe renal, hepatic, or adrenocortical impairment. Hyperchloremic acidosis. Cirrhosis. Chronic noncongestive angle-closure glaucoma. Sulfonamide allergy.
Respiratory impairment. Renal calcium calculi. Diabetes. Gout. Test blood periodically in chronic use. Pregnancy (Cat.C). Nursing mothers: not recommended.
May inhibit renal excretion of basic drugs and promote excretion of acidic drugs. May increase salicylate toxicity (acidosis). Hypokalemia with corticosteroids, potassium wasting diuretics.
Carbonic anhydrase inhibitor.
Anorexia, drowsiness, confusion, malaise, depression, GI distress, paresthesias, tinnitus, acidosis, initial hypokalemia, hyperuricemia, transient myopia; renal calculi, nephrotoxicity, hepatic dysfunction, blood dyscrasias, rash, fever, photosensitivity (rare).
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