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Dextroamphetamine sulfate tablets
ADHD
Sleep-wake disorders
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Drug Name:

Dextroamphetamine sulfate tablets CII

Generic Name and Formulations:
Dextroamphetamine sulfate 5mg, 10mg; scored tabs.

Company:
Various generic manufacturers

Therapeutic Use:

Indications for Dextroamphetamine sulfate tablets:

Attention deficit hyperactivity disorder.

Adult:

Not recommended.

Children:

Avoid late evening doses; give first dose upon awakening and 1–2 more doses 4–6 hrs apart. <3yrs: not recommended. 3–5yrs: initially 2.5mg daily; may increase by 2.5mg at weekly intervals. ≥6yrs: initially 5mg 1–2 times daily; may increase by 5mg at weekly intervals; usual max 40mg/day.

Contraindications:

Advanced arteriosclerosis. Cardiovascular disease. Moderate to severe hypertension. Hyperthyroidism. Glaucoma. Drug or alcohol abuse. Agitation. During or within 14 days of MAOIs. Hypersensitivity to sympathomimetics.

Warnings/Precautions:

Tourette's syndrome. Psychosis. Mild hypertension. Seizure disorders. Monitor growth in children. Reevaluate need for therapy after drug-free interval. Prescribe limited quantity. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

Hypertensive crisis with MAOIs: see Contraindications. Potentiated by urinary alkalinizers (eg, some thiazides), tricyclic antidepressants, propoxyphene. Potentiates meperidine, norepinephrine, phenobarbital, phenytoin. Antagonized by acidifiers, psychotropics, lithium. Antagonizes adrenergic blockers, sedatives, antihypertensives. Monitor phenytoin, ethosuximide, phenobarbital. Convulsions with propoxyphene overdose and amphetamines. May interfere with urinary steroid tests.

Pharmacological Class:

Amphetamine.

Adverse Reactions:

Hypertension, tachycardia, CNS overstimulation, dry mouth, GI disorders, anorexia, urticaria.

Note:

Formerly known under the brand name Dextrostat.

How Supplied:

Contact supplier.

Indications for Dextroamphetamine sulfate tablets:

Narcolepsy.

Adult:

Avoid late evening doses. 5–60mg daily in divided doses.

Children:

Avoid late evening doses; give first dose upon awakening and 1–2 more doses 4–6 hrs apart. <6yrs: not recommended. 6–12yrs: initially 5mg daily; may increase by 5mg at weekly intervals. ≥12yrs: initially 10mg daily; may increase by 10mg at weekly intervals.

Contraindications:

Advanced arteriosclerosis. Cardiovascular disease. Moderate to severe hypertension. Hyperthyroidism. Glaucoma. Drug or alcohol abuse. Agitation. During or within 14 days of MAOIs. Hypersensitivity to sympathomimetics.

Warnings/Precautions:

Tourette's syndrome. Psychosis. Mild hypertension. Seizure disorders. Monitor growth in children. Reevaluate need for therapy after drug-free interval. Prescribe limited quantity. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

Hypertensive crisis with MAOIs: see Contraindications. Potentiated by urinary alkalinizers (eg, some thiazides), tricyclic antidepressants, propoxyphene. Potentiates meperidine, norepinephrine, phenobarbital, phenytoin. Antagonized by acidifiers, psychotropics, lithium. Antagonizes adrenergic blockers, sedatives, antihypertensives. Monitor phenytoin, ethosuximide, phenobarbital. Convulsions with propoxyphene overdose and amphetamines. May interfere with urinary steroid tests.

Pharmacological Class:

Amphetamine.

Adverse Reactions:

Hypertension, tachycardia, CNS overstimulation, dry mouth, GI disorders, anorexia, urticaria.

Note:

Formerly known under the brand name Dextrostat.

How Supplied:

Contact supplier.

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