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Hyperacidity, GERD, and ulcers
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Drug Name:


Generic Name and Formulations:
Misoprostol 100mcg, 200mcg; tabs.

Pfizer Inc.

Therapeutic Use:

Indications for CYTOTEC:

Prevention of NSAID-induced gastric ulcers.


Take with food. 200mcg 4 times daily with meals (last dose at bedtime). May reduce dose if not tolerated.


Not established.


Pregnancy (Cat.X).


Can cause birth defects, abortion, premature birth or uterine rupture in pregnant women. For women of childbearing potential: negative serum pregnancy test within 2 weeks before starting therapy; begin on 2nd or 3rd day of next menstrual period; maintain contraception during therapy; give oral and written warnings on risks in pregnancy. Cardiovascular disease. Inflammatory bowel disease. Dehydration. Labor & delivery. Nursing mothers.


Avoid magnesium-containing antacids (to reduce diarrhea risk). Concomitant oxytocic agents: not recommended.

Pharmacological Class:

Prostaglandin E1 analogue.

Adverse Reactions:

Diarrhea, abdominal pain, headache, gynecological effects (eg, spotting, cramps), abortion, premature birth, birth defects, uterine rupture.

How Supplied:

Tabs 100mcg—60, 120; 200mcg—60, 100

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