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Skin infections (topicals)
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Drug Name:


Generic Name and Formulations:
Hydrocortisone acetate 0.5%, polymyxin B (as sulfate) 10000 Units/g, neomycin (as sulfate) 0.35%; crm.

Pfizer Inc.

Therapeutic Use:

Indications for CORTISPORIN:

Short-term use in corticosteroid-responsive dermatoses with secondary infection.


Apply sparingly and massage in 2–4 times daily.


Not recommended.


Do not use in eyes, external ear canal if eardrum perforated. Tuberculous, fungal, or viral lesions.


Intertrigo, diaper or stasis dermatitis or ulceration, extensive burns (neomycin may be absorbed). Avoid prolonged use or on large areas. Use lowest effective dose. Monitor for HPA axis suppression; avoid abrupt cessation if used for chronic conditions. Discontinue if infection persists or worsens or if superinfection occurs. Occlusion: not recommended. Pregnancy (Cat.C). Nursing mothers.

See Also:


Pharmacological Class:

Steroid + antibiotics.

Adverse Reactions:

Local irritation, folliculitis, hypertrichosis, dermatitis, sensitization, ototoxicity, nephrotoxicity (if neomycin is significantly absorbed), HPA axis suppression (esp. in children), epidermal and dermal atrophy (esp. in thin-skinned or occluded areas).

How Supplied:

Crm—7.5g; Oint—½oz

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