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CORGARD
Angina
Hypertension
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Drug Name:

CORGARD Rx

Generic Name and Formulations:
Nadolol 20mg, 40mg, 80mg; scored tabs.

Company:
Pfizer Inc.

Therapeutic Use:

Indications for CORGARD:

Long-term management of angina.

Adult:

Initially 40mg once daily. May increase at 3–7 day intervals. Usual maintenance: 40–80mg once daily; max 240mg daily. Renal impairment: reduce dosage, see full labeling.

Children:

Not recommended.

Contraindications:

Asthma. Sinus bradycardia. 2nd- or 3rd-degree AV block. Overt heart failure. Cardiogenic shock. CHF.

Warnings/Precautions:

Ischemic heart disease. Bronchospastic disease, COPD. Renal or hepatic dysfunction. Diabetes. Hyperthyroidism. Surgery. SLE. Avoid abrupt cessation. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

Hypotension, bradycardia with catecholamine-depleting drugs, general anesthetics. May increase cardiac effects of calcium channel blockers, digitalis. Antagonized by NSAIDs. Adjust antidiabetic medications. May interfere with glaucoma screening tests. May block epinephrine.

Pharmacological Class:

Beta-blocker.

Adverse Reactions:

Bradycardia, dizziness, fatigue, cold extremities, heart failure, heart block, bronchospasm, GI upset, rash, pruritus.

How Supplied:

Tabs—100

Indications for CORGARD:

Hypertension.

Adult:

Initially 40mg once daily. Usual maintenance: 40–80mg once daily; max 320mg daily. Renal impairment: reduce dosage, see full labeling.

Children:

Not recommended.

Contraindications:

Asthma. Sinus bradycardia. 2nd- or 3rd-degree AV block. Overt heart failure. Cardiogenic shock. CHF.

Warnings/Precautions:

Ischemic heart disease. Bronchospastic disease, COPD. Renal or hepatic dysfunction. Diabetes. Hyperthyroidism. Surgery. SLE. Avoid abrupt cessation. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

Hypotension, bradycardia with catecholamine-depleting drugs, general anesthetics. May increase cardiac effects of calcium channel blockers, digitalis. Antagonized by NSAIDs. Adjust antidiabetic medications. May interfere with glaucoma screening tests. May block epinephrine.

Pharmacological Class:

Beta-blocker.

Adverse Reactions:

Bradycardia, dizziness, fatigue, cold extremities, heart failure, heart block, bronchospasm, GI upset, rash, pruritus.

How Supplied:

Tabs—100

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