Generic Name and Formulations:
Various generic manufacturers
Susceptible urinary tract, skin and skin structure infections, pharyngitis/tonsillitis, impetigo.
Uncomplicated UTI: 1–2g once daily or in 2 divided doses. Complicated UTI: 2g/day in 2 divided doses. Skin and skin structure infections: 1g once daily or in 2 divided doses. Pharyngitis/tonsillitis: 1g once daily or in 2 divided doses for 10 days. Renal dysfunction (CrCl <50mL/min): 1g loading dose, then 500mg at increased dosing intervals (see literature). Continue for 3 days after symptoms improve.
UTI, skin and skin structure infections: 30mg/kg/day in 2 divided doses every 12 hours. Pharyngitis/tonsillitis, impetigo: 30mg/kg once daily or in 2 divided doses for 10 days. Renal dysfunction: reduce dose (see literature). Continue for 3 days after symptoms improve.
Penicillin or other allergy. Discontinue if colitis occurs and treat. Impaired renal function (CrCl <50mL/min). GI disease (esp. colitis). Pregnancy (Cat.B). Nursing mothers.
Potentiated by probenecid. May cause false (+) Clinitest or Coomb's test.
GI upset, anaphylaxis, rash; blood dyscrasias (rare).
Formerly known under the brand names Duricef, Ultracef.
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