This site is intended for healthcare professionals


Select the drug indication to add to your list

Erectile dysfunction
Compare To Related Drugs
View/Edit/Compare Drugs In My List

Only 4 drugs may be compared at once

Drug Name:


Generic Name and Formulations:
Alprostadil 5mcg, 10mcg, 20mcg, 40mcg; per vial; lyophilized pwd for intracavernous inj after reconstitution; contains benzyl alcohol.

Pfizer Inc.

Therapeutic Use:

Indications for CAVERJECT:

Treatment of erectile dysfunction. Adjunct to other diagnostic tests in the diagnosis of erectile dysfunction.


Inject into the dorso-lateral aspect of the proximal third of penis, avoid visible veins; rotate inj side and site. Determine optimum dose in office. If no response, may give 2nd dose after 1hr; if partial response occurs, wait 24hrs before next dose. Vasculogenic, psychogenic, or mixed etiology: initially 2.5mcg; if partial response, may give 2nd dose of 5mcg; may increase in increments of 5–10mcg until desired response. If no response to 1st dose, may give 2nd dose of 7.5mcg within 1hr; may increase in increments of 5–10mcg until desired response. Neurogenic etiology: initially 1.25mcg; may give 2nd dose of 2.5mcg, and 3rd dose of 5mcg; may increase in increments of 5mcg until desired response. Usual max: 60mcg and 3 inj/week; allow at least 24hrs between doses. Reduce dose if erection lasts over 1hr. Adjunct in diagnosis: see full labeling.


Not indicated; see Contraindications.


Predisposition to priapism. Anatomical penile deformation. Penile implants. Patients for whom sexual activity is inadvisable or contraindicated. Women. Children. Newborns.


Preexisting cardiovascular disease. Evaluate and treat underlying causes prior to initiating therapy. Treat priapism immediately. Patient must not adjust dose on own. Reevaluate every 3 months. Significant corpora cavernosa venous leakage. Monitor for signs of penile fibrosis. Discontinue if penile angulation, cavernosal fibrosis, or Peyronie's disease develops. Risk of needle breakage; use proper handling and injection techniques.


Concomitant vasoactive agents: not recommended. Caution with anticoagulants.

Pharmacological Class:


Adverse Reactions:

Penile pain, prolonged erection, priapism, penile fibrosis, inj site hematoma or ecchymosis, prostatic disorder, penile rash or edema, other local effects, upper respiratory infection, hypertension, headache, increased risk of blood-borne diseases, others.

How Supplied:

Vials—6; Caverject Impulse 10mcg, 20mcg—2 (dual chamber syringe systems + supplies)

Join MIMS Learning now to manage all your CPD and notes in one place!

By registering you agree with our Terms and Conditions and Privacy Policy.

Already a MIMS Learning member?

Sign In Now »
Red flag CPD modules
0.50 Credits
Red flags

Fever in adults - red flag symptomsExternal web site

Fever in adults can have potentially serious causes, ranging from sepsis to malignancy. Dr Pipin Singh...

0.50 Credits
Red flags

Bone pain - red flag symptomsExternal web site

In this article Dr Pipin Singh advises on how to identify red flags in patients presenting with bone...

0.50 Credits
Red flags

Pregnancy - red flag symptomsExternal web site

Dr Matthew West covers the red flags to look out for in pregnancy, including back pain, bleeding, headaches...

Font Awesome Icons
View more
Clinical review CPD modules
1.50 Credits
Clinical Review

Bronchiectasis: clinical reviewExternal web site

This article, updated in 2016 by Dr Anthony De Soyza, advises on causes, investigations and managing...

1.50 Credits
Clinical Review

Brugada syndrome: clinical reviewExternal web site

Dr Keith Barnard discusses the aetiology and symptoms of Brugada syndrome. Key learning points for GPs...

1.50 Credits
Clinical Review

Measles: clinical reviewExternal web site

Dr Kirsty Le Doare and Dr Nuria Martinez-Alier describe the signs and symptoms of measles and outline...

Font Awesome Icons
View more

is free, fast, and customized just for you!

Already a member?

Sign In Now »