Generic Name and Formulations:
Fluorouracil 0.5% (0.35% in microspheres); crm.
Valeant Pharmaceuticals, Inc
Multiple actinic or solar keratoses of the face and anterior scalp.
≥18yrs: Wash and dry area. Wait 10 minutes. Apply thin film to skin where lesions appear once daily for up to 4 weeks. Do not occlude. May apply sunscreen/ moisturizer 2 hours later. Wash hands after use.
<18yrs: not recommended.
Dihydropyrimidine dehydrogenase (DPD) deficiency. Women of childbearing potential. Pregnancy (Cat.X).
Discontinue if symptoms of DPD deficiency develop (e.g., abdominal pain, bloody diarrhea, vomiting, fever, chills). Ulcerated or inflamed skin. Avoid eyes, mucous membranes, exposure to sun or UV light. Nursing mothers: not recommended.
Application site reaction (may persist 2 weeks after drug is stopped), eye irritation.
Join MIMS Learning now to manage all your CPD and notes in one place!
Already a MIMS Learning member?Sign In Now »
This red flags article explains signs and symptoms of potentially serious pathology in patients presenting...
This article by Dr Tillmann Jacobi covers the possible red flag symptoms to consider when a patient...
Dr Suneeta Kochhar provides an overview of red flag symptoms in patients presenting with headaches...
In this article, Dr David Brass and Dr Neil Rajan discuss the risk factors for BCC, making the diagnosis...
This article by Dr Rajiv Sankaranarayanan covers the diagnosis and management of cardiomyopathy. Key...
Dr Benjamin Simpson provides an in-depth overview of Parkinson’s disease, including information on risk...