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BUTISOL SODIUM ORAL SOLUTION
Anxiety/OCD
Sleep-wake disorders
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Drug Name:

BUTISOL SODIUM ORAL SOLUTION CIII

Generic Name and Formulations:
Butabarbital sodium 30mg/5mL; contains alcohol 7%, tartrazine.

Company:
Meda Pharmaceuticals

Therapeutic Use:

Indications for BUTISOL SODIUM ORAL SOLUTION:

For use as a sedative or hypnotic.

Adult:

15–30mg 3 or 4 times daily. Pre-op sedative: 50–100mg 60–90 minutes before surgery. Elderly, debilitated, hepatic or renal impairment: reduce dose.

Children:

Pre-op sedative: 2–6mg/kg, max 100mg.

Contraindications:

Manifest or latent porphyria.

Warnings/Precautions:

Premonitory signs of hepatic coma: not recommended. Renal or hepatic impairment. Acute or chronic pain. Depression. Suicidal tendencies. Drug or alcohol abuse. Monitor hematopoietic, renal, hepatic systems with long-term therapy. Avoid abrupt cessation. Write ℞ for smallest practical amount. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat. D); may cause fetal damage. Nursing mothers.

Interactions:

Avoid concomitant griseofulvin. May antagonize oral anticoagulants (eg, warfarin), corticosteroids (may require dosage adjustments), doxycycline (monitor), oral contraceptives (consider alternative contraceptive method). May be potentiated by sodium valproate, valproic acid, MAOIs. Additive CNS depressant effects with alcohol, other CNS depressants. Concomitant phenytoin: monitor blood levels frequently.

See Also:

BUTISOL SODIUM

Pharmacological Class:

Barbiturate.

Adverse Reactions:

Somnolence, agitation, confusion, hyperkinesia, ataxia, CNS depression, nightmares, nervousness, psychiatric disturbance, sleep-driving, hallucination, insomnia, anxiety, dizziness, abnormal thinking, hypoventilation, apnea, bradycardia, hypotension, syncope, GI upset, constipation, headache, hypersensitivity reactions (eg, angioedema: do not rechallenge if occurs), fever, liver damage.

How Supplied:

Tabs—100; Oral soln—pint

Indications for BUTISOL SODIUM ORAL SOLUTION:

For use as a sedative or hypnotic.

Adult:

50–100mg at bedtime. Limit use to 2 weeks. Elderly, debilitated, hepatic or renal impairment: reduce dose.

Children:

Not recommended.

Contraindications:

Manifest or latent porphyria.

Warnings/Precautions:

Premonitory signs of hepatic coma: not recommended. Renal or hepatic impairment. Acute or chronic pain. Depression. Suicidal tendencies. Drug or alcohol abuse. Monitor hematopoietic, renal, hepatic systems with long-term therapy. Avoid abrupt cessation. Write ℞ for smallest practical amount. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat. D); may cause fetal damage. Nursing mothers.

Interactions:

Avoid concomitant griseofulvin. May antagonize oral anticoagulants (eg, warfarin), corticosteroids (may require dosage adjustments), doxycycline (monitor), oral contraceptives (consider alternative contraceptive method). May be potentiated by sodium valproate, valproic acid, MAOIs. Additive CNS depressant effects with alcohol, other CNS depressants. Concomitant phenytoin: monitor blood levels frequently.

See Also:

BUTISOL SODIUM

Pharmacological Class:

Barbiturate.

Adverse Reactions:

Somnolence, agitation, confusion, hyperkinesia, ataxia, CNS depression, nightmares, nervousness, psychiatric disturbance, sleep-driving, hallucination, insomnia, anxiety, dizziness, abnormal thinking, hypoventilation, apnea, bradycardia, hypotension, syncope, GI upset, constipation, headache, hypersensitivity reactions (eg, angioedema: do not rechallenge if occurs), fever, liver damage.

How Supplied:

Tabs—100; Oral soln—pint

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