This site is intended for healthcare professionals


Select the drug indication to add to your list

Migraine and headache
Compare To Related Drugs
View/Edit/Compare Drugs In My List

Only 4 drugs may be compared at once

Drug Name:

Butalbital/Acetaminophen Rx

Generic Name and Formulations:
Butalbital 50mg, acetaminophen 325mg; tabs.

Various generic manufacturers

Therapeutic Use:

Indications for Butalbital/Acetaminophen:

Tension (or muscle contraction) headache.


1–2 tabs every 4 hours; max 6 tabs daily.


Not recommended.




Extended use: not recommended. Severe renal or hepatic impairment. Acute abdominal conditions. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers: not recommended.


Potentiated by alcohol, other CNS depressants, MAOIs. May cause false (+) urine test for 5-hydroxyindoleacetic acid.

Pharmacological Class:

Barbiturate + analgesic.

Adverse Reactions:

Drowsiness, dizziness, paradoxical excitement, rash; overdosage: respiratory depression, hepatotoxicity.


Formerly known under the brand name Phrenilin.

How Supplied:

Contact supplier.

Join MIMS Learning now to manage all your CPD and notes in one place!

By registering you agree with our Terms and Conditions and Privacy Policy.

Already a MIMS Learning member?

Sign In Now »
Red flag CPD modules
0.50 Credits
Red flags

Fever in adults - red flag symptomsExternal web site

Fever in adults can have potentially serious causes, ranging from sepsis to malignancy. Dr Pipin Singh...

0.50 Credits
Red flags

Bone pain - red flag symptomsExternal web site

In this article Dr Pipin Singh advises on how to identify red flags in patients presenting with bone...

0.50 Credits
Red flags

Pregnancy - red flag symptomsExternal web site

Dr Matthew West covers the red flags to look out for in pregnancy, including back pain, bleeding, headaches...

Font Awesome Icons
View more
Clinical review CPD modules
1.50 Credits
Clinical Review

Bronchiectasis: clinical reviewExternal web site

This article, updated in 2016 by Dr Anthony De Soyza, advises on causes, investigations and managing...

1.50 Credits
Clinical Review

Brugada syndrome: clinical reviewExternal web site

Dr Keith Barnard discusses the aetiology and symptoms of Brugada syndrome. Key learning points for GPs...

1.50 Credits
Clinical Review

Measles: clinical reviewExternal web site

Dr Kirsty Le Doare and Dr Nuria Martinez-Alier describe the signs and symptoms of measles and outline...

Font Awesome Icons
View more

is free, fast, and customized just for you!

Already a member?

Sign In Now »