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Bumetanide Inj
Edema
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Drug Name:

Bumetanide Inj Rx

Generic Name and Formulations:
Bumetanide 0.25mg/mL; contains benzyl alcohol.

Company:
Various generic manufacturers

Therapeutic Use:

Indications for Bumetanide Inj:

Edema.

Adult:

Initially 0.5–1mg IM or IV. May give 1–2 more doses at 2–3 hour intervals; max 10mg/day.

Children:

<18yrs: not recommended.

Contraindications:

Anuria. Infants. Hepatic coma. Severe electrolyte depletion.

Warnings/Precautions:

Hepatic cirrhosis. Ascites. Progressive renal disease. Gout. Diabetes. Postsympathectomy. Monitor electrolytes, blood, liver function. May need K+ supplementation. K+ losing nephropathy. Discontinue if renal dysfunction progresses. Aldosterone excess. Ventricular arrhythmias. Elderly. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

May increase digitalis, lithium toxicity. Hypokalemia with digitalis, diuretics in CHF. Alcohol, CNS depressants increase orthostatic hypotension. Avoid probenecid, indomethacin. Ototoxicity may be potentiated with aminoglycosides.

Pharmacological Class:

Diuretic (loop).

Adverse Reactions:

Muscle cramps, dizziness, hypotension, headache, nausea, encephalopathy, ototoxicity, rash, fluid or electrolyte imbalance, hyperglycemia, hyperuricemia, blood dyscrasias.

Note:

Formerly known under the brand name Bumex.

How Supplied:

Contact supplier.

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