Generic Name and Formulations:
Penicillin G benzathine 900,000 units, penicillin G procaine 300,000 units; per syringe; susp for deep IM inj; contains parabens.
Susceptible moderately severe infections including respiratory, skin and soft tissue, erysipelas, scarlet fever, otitis media.
Use other strengths.
Give by deep IM inj into midlateral thigh or buttock. Group A strep: one inj of 900/300 once. Pneumococcal: one inj of 900/300 every 2–3 days until afebrile for 48 hours.
Avoid intraarterial, intravascular, and intraneural inj.
Not for IV use. Cephalosporin, imipenem, or other allergy: not recommended. Asthma. Monitor renal and hematopoietic function in prolonged use. Pregnancy (Cat.B). Nursing mothers.
Potentiated by probenecid. May cause false (+) glucose test with Clinitest.
Rash, drug fever, serum sickness, anaphylaxis, blood dyscrasias, neuropathy, nephropathy, inj site reactions.
C–R Tubex 600,000 units/mL (1mL, 2mL)—10 (w. 1 inch or 1.25 inch needles); C–R disposable syringe 600,000 units/mL (4mL)—10 (w. 2 inch needles); C–R 900/300 Tubex 1.2 million units/syringe (2mL)—10 (w. 1 inch or 1.25 inch needles)
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