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BICILLIN C-R 900/300
Bacterial infections
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Drug Name:

BICILLIN C-R 900/300 Rx

Generic Name and Formulations:
Penicillin G benzathine 900,000 units, penicillin G procaine 300,000 units; per syringe; susp for deep IM inj; contains parabens.

Pfizer Inc.

Therapeutic Use:

Indications for BICILLIN C-R 900/300:

Susceptible moderately severe infections including respiratory, skin and soft tissue, erysipelas, scarlet fever, otitis media.


Use other strengths.


Give by deep IM inj into midlateral thigh or buttock. Group A strep: one inj of 900/300 once. Pneumococcal: one inj of 900/300 every 2–3 days until afebrile for 48 hours.


Avoid intraarterial, intravascular, and intraneural inj.


Not for IV use. Cephalosporin, imipenem, or other allergy: not recommended. Asthma. Monitor renal and hematopoietic function in prolonged use. Pregnancy (Cat.B). Nursing mothers.


Potentiated by probenecid. May cause false (+) glucose test with Clinitest.

See Also:


Pharmacological Class:

Penicillinase-sensitive penicillin.

Adverse Reactions:

Rash, drug fever, serum sickness, anaphylaxis, blood dyscrasias, neuropathy, nephropathy, inj site reactions.

How Supplied:

C–R Tubex 600,000 units/mL (1mL, 2mL)—10 (w. 1 inch or 1.25 inch needles); C–R disposable syringe 600,000 units/mL (4mL)—10 (w. 2 inch needles); C–R 900/300 Tubex 1.2 million units/syringe (2mL)—10 (w. 1 inch or 1.25 inch needles)

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