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Benztropine
Parkinsonism
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Drug Name:

Benztropine Rx

Generic Name and Formulations:
Benztropine mesylate 0.5mg, 1mg, 2mg; scored tabs.

Company:
Various generic manufacturers

Therapeutic Use:

Indications for Benztropine:

Adjunct in Parkinsonism, drug-induced extrapyramidal disorders.

Adult:

Parkinsonism: initially 0.5–1mg at bedtime. May increase by 0.5mg at 5–6 day intervals; max 6mg daily. Extrapyramidal disorders: 1–4mg 1–2 times daily. Acute dystonic reactions: 1–2mg IM or IV.

Children:

See Contraindications. Use cautiously in older children.

Contraindications:

Children <3yrs old.

Warnings/Precautions:

Tardive dyskinesia: not recommended. Narrow-angle glaucoma. Tachycardia. Psychosis. Prostatic hypertrophy. GI or GU obstruction. Chronically ill. Alcoholics. CNS disease. Exposure to extreme heat. Elderly. Pregnancy.

Interactions:

Paralytic ileus, hyperthermia, heat stroke with phenothiazines, tricyclic antidepressants. Antagonizes psychotropics.

See Also:

COGENTIN INJECTION

Pharmacological Class:

Anticholinergic.

Adverse Reactions:

Anticholinergic and antihistaminic effects, weakness, confusion, anhidrosis, excitement, GI upset, depression, lethargy, heat stroke, dysuria, toxic psychosis, rash.

Note:

Tabs formerly known under the brand name Cogentin.

How Supplied:

Tabs—contact supplier; Amps—(5 x 2mL)

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