This site is intended for healthcare professionals


Select the drug indication to add to your list

Migraine and headache
Compare To Related Drugs
View/Edit/Compare Drugs In My List

Only 4 drugs may be compared at once

Drug Name:


Generic Name and Formulations:
Codeine phosphate 30mg, butalbital 50mg, aspirin 325mg, caffeine 40mg; caps.

Breckenridge Pharmaceutical, Inc.

Therapeutic Use:

Indications for ASCOMP w. CODEINE:

Tension (or muscle contraction) headache.


1–2 caps every 4 hours, as needed; max 6 caps/day. Use lowest effective dose for shortest period of time.


Not recommended.


NSAID allergy. Porphyria. Bleeding or coagulation disorders. Peptic ulcer.


Renal or hepatic impairment; monitor liver/renal function tests. Acute abdomen. Asthma. Bleeding disorders. Head injury. Increased intracranial pressure. Impaired thyroid or adrenocortical function. GI or GU obstruction. Ultra-rapid metabolizers of codeine (may experience overdose symptoms). Drug abusers. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat.C). Nursing mothers: not recommended.


CNS effects may be enhanced by MAOIs. Concomitant corticosteroids: withdrawal of corticosteroid may result in salicylism. May potentiate oral anticoagulants, oral antidiabetics and insulin, 6-mercaptopurine and methotrexate, NSAIDs, other narcotic analgesics, alcohol, general anesthetics, tranquilizers, sedative-hypnotics, other CNS depressants. May diminish effects of uricosuric agents.

Pharmacological Class:

Opioid + barbiturate + salicylate + stimulant.

Adverse Reactions:

Drowsiness, dizziness, intoxicated feeling, GI upset/pain.

How Supplied:

Caps—100, 500

Join MIMS Learning now to manage all your CPD and notes in one place!

By registering you agree with our Terms and Conditions and Privacy Policy.

Already a MIMS Learning member?

Sign In Now »
Red flag CPD modules
0.50 Credits
Red flags

Fever in adults - red flag symptomsExternal web site

Fever in adults can have potentially serious causes, ranging from sepsis to malignancy. Dr Pipin Singh...

0.50 Credits
Red flags

Bone pain - red flag symptomsExternal web site

In this article Dr Pipin Singh advises on how to identify red flags in patients presenting with bone...

0.50 Credits
Red flags

Pregnancy - red flag symptomsExternal web site

Dr Matthew West covers the red flags to look out for in pregnancy, including back pain, bleeding, headaches...

Font Awesome Icons
View more
Clinical review CPD modules
1.50 Credits
Clinical Review

Bronchiectasis: clinical reviewExternal web site

This article, updated in 2016 by Dr Anthony De Soyza, advises on causes, investigations and managing...

1.50 Credits
Clinical Review

Brugada syndrome: clinical reviewExternal web site

Dr Keith Barnard discusses the aetiology and symptoms of Brugada syndrome. Key learning points for GPs...

1.50 Credits
Clinical Review

Measles: clinical reviewExternal web site

Dr Kirsty Le Doare and Dr Nuria Martinez-Alier describe the signs and symptoms of measles and outline...

Font Awesome Icons
View more

is free, fast, and customized just for you!

Already a member?

Sign In Now »