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ARNUITY ELLIPTA
Asthma/COPD
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Drug Name:

ARNUITY ELLIPTA Rx

Generic Name and Formulations:
Fluticasone furoate 100mcg, 200mcg; per inhalation; dry pwd for oral inhalation.

Company:
GlaxoSmithKline

Therapeutic Use:

Indications for ARNUITY ELLIPTA:

Maintenance treatment of asthma as prophylactic therapy.

Limitations Of use:

Not for relief of acute bronchospasm.

Adult:

Base initial dose on previous asthma therapy and disease severity. Not on inhaled corticosteroid: usually initiate at 100mcg once daily; may increase to 200mcg once daily if inadequate response after 2 weeks. Max 200mcg/day. Rinse mouth after use.

Children:

Not established.

Contraindications:

Primary treatment of status asthmaticus or acute asthma episodes. Severe hypersensitivity to milk proteins.

Warnings/Precautions:

Do not exceed recommended dose. Prescribe a short-acting, inhaled β2-agonist for acute symptoms; monitor for increased need. Immunosuppressed. Tuberculosis. Systemic infections (eg, fungal, bacterial, viral, parasitic). Ocular herpes simplex. If exposed to chickenpox or measles, consider immune globulin or antiviral prophylactic therapies. Monitor for adrenal insufficiency when transferring from systemic steroids. Reevaluate periodically. Monitor for hypercorticism and HPA axis suppression (if occurs, discontinue gradually), growth in children, intraocular pressure, glaucoma, or cataracts. Discontinue if paradoxical bronchospasm occurs; use alternative therapy. Assess bone mineral density if risk factors exist (eg, prolonged immobilization, history of osteoporosis). Moderate or severe hepatic impairment; monitor. Elderly. Labor and delivery. Pregnancy (Cat.C). Nursing mothers.

Interactions:

Caution with concomitant strong CYP3A4 inhibitors (eg, ketoconazole, ritonavir, clarithromycin, conivaptan, indinavir, itraconazole, lopinavir, nefazodone, nelfinavir, saquinavir, telithromycin, troleandomycin, voriconazole).

Pharmacological Class:

Corticosteroid.

Adverse Reactions:

Nasopharyngitis, upper respiratory tract infection, headache, bronchitis, oral candidiasis; hypersensitivity reactions (discontinue if occurs).

How Supplied:

Dry pwd inhaler—30 doses

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