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Drug Name:


Generic Name and Formulations:
Brimonidine tartrate 0.1%, 0.15%; oph. soln; contains purite.


Therapeutic Use:

Indications for ALPHAGAN P:

Open-angle glaucoma. Ocular hypertension.

Adults and Children:

<2yrs: not recommended. ≥2yrs: 1 drop every 8 hours.


Concomitant MAOIs.


Severe cardiovascular disease. Hepatic or renal impairment. Depression. Cerebral or coronary insufficiency. Raynaud's phenomenon. Orthostatic hypotension. Thromboangiitis obliterans. Remove soft contact lenses before use; may reinsert 15 minutes later. Monitor for loss of effect. Pregnancy (Cat.B). Nursing mothers: not recommended.


MAOIs: see Contraindications. Caution with CNS depressants, antihypertensives, cardiac glycosides, tricyclic antidepressants. Separate administration of other oph drugs by ≥5 minutes.

Pharmacological Class:

Alpha-2 agonist.

Adverse Reactions:

Oral dryness, ocular hyperemia, burning, stinging, headache, blurred or abnormal vision, foreign body sensation, fatigue, drowsiness, conjunctival follicles, ocular allergic reactions or pruritus, corneal staining/erosion, photophobia, ocular discomfort or dryness, tearing, upper respiratory symptoms, conjunctival blanching, muscular pain, others.

How Supplied:

Soln—5mL, 10mL, 15mL

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