Generic Name and Formulations:
Biperiden HCl 2mg; tabs.
Adjunct in the therapy of all forms of parkinsonism (eg, idiopathic, postencephalitic, arteriosclerotic). To control extrapyramidal disorders secondary to neuroleptic drug therapy (eg, phenothiazines).
Parkinson's disease: 2mg three or four times daily. Individualize and titrate upward to max 16mg/24 hours. Extrapyramidal disorders: 2mg one to three times daily.
Narrow angle glaucoma. Bowel obstruction. Megacolon.
Glaucoma. Prostatism. Epilepsy. Arrhythmia. Pregnancy (Cat.C). Nursing mothers.
Avoid concomitant alcohol. Potentiated anticholinergic effects with drugs that have secondary anticholinergic actions (eg, narcotics analgesics, phenothiazines, tricyclic antidepressants, antiarrhythmics, antihistamines).
Anticholinergic effects (eg, dry mouth, blurred vision, drowsiness, euphoria, disorientation, urinary retention, postural hypotension, constipation, agitation, disturbed behavior); rare: generalized choreic movements, reduction in REM sleep.
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