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ADVIL PM
Sleep-wake disorders
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Drug Name:

ADVIL PM OTC

Generic Name and Formulations:
Ibuprofen 200mg, diphenhydramine citrate 38mg; caplets.

Company:
Pfizer Consumer Healthcare

Therapeutic Use:

Indications for ADVIL PM:

Relief of occasional sleeplessness when associated with minor aches and pains.

Adult:

2 caplets or liqui-gels at bedtime. Max 2 caplets or liqui-gels/24hrs.

Children:

<12yrs: not recommended.

Contraindications:

Aspirin allergy. Unless sufficient time for a full night's sleep. Immediately before or after cardiac surgery. Sleeplessness without pain. Concomitant with other diphenhydramine-containing products (including topicals).

Warnings/Precautions:

Increased risk of severe stomach bleeding (esp. ≥60yrs old). History of GI disorders (eg, heartburn, bleeding ulcers). Respiratory disorders (eg, emphysema, bronchitis). Increased risk of heart attack or failure, and stroke. Hypertension. Heart disease. Recent stroke. Liver cirrhosis. Renal disease. Asthma. Glaucoma. GI or urinary obstruction. Reevaluate if pain persists or worsens after >10 days or sleeplessness persists continuously >2 weeks. Elderly. Pregnancy (avoid during 3rd trimester). Nursing mothers.

Interactions:

Avoid aspirin or other pain relievers. Increased risk of GI bleed with anticoagulants, corticosteroids, other OTC or Rx NSAID-containing products (eg, ibuprofen, naproxen, others), ≥3 alcoholic drinks/day, or prolonged use. Caution with diuretics. Additive effects with other antihistamines, anticholinergics, sedatives, tranquilizers, or any other sleep-aid.

See Also:

ADVIL PM LIQUI-GELS

Pharmacological Class:

NSAID + hypnotic (anticholinergic).

Adverse Reactions:

Drowsiness, GI upset/bleed, rash, symptoms of heart problems or stroke (eg, trouble breathing, feel faint, slurred speech), redness, swelling, allergic reactions; discontinue if occur.

How Supplied:

Caplets—20, 40, 80, 120 (orig or EZ open); Liqui-Gels—20, 40, 80

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