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Drug Name:


Generic Name and Formulations:
Nifedipine 30mg, 60mg, 90mg; ext rel tabs.

Bayer Healthcare Pharmaceuticals Inc.

Therapeutic Use:

Indications for ADALAT CC:



Swallow whole on empty stomach. Initially 30mg once daily. Usual maintenance: 30–60mg once daily. Titrate over 7–14 days; max 90mg/day.


Not recommended.


Aortic stenosis. Angina. Severe obstructive coronary artery disease. Heart failure. Surgery. Pregnancy (Cat.C). Nursing mothers: not recommended.


Potentiates antihypertensives, digoxin, tacrolimus. Angina and heart failure possible with β-blockers. Potentiated by cimetidine, doxazosin, ketoconazole, valproic acid, grapefruit juice, other CYP3A4 inhibitors. Antagonized by rifampin, phenytoin, carbamazepine, St. John's wort, other CYP3A4 inducers. Monitor oral anticoagulants, quinidine. Hypotension possible with fentanyl.

Pharmacological Class:

Calcium channel blocker (CCB) (dihydropyridine).

Adverse Reactions:

Peripheral edema, headache, flushing, dizziness, fatigue, constipation, muscle cramps, rash; exacerbation of angina, heart failure (rare).

How Supplied:


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