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Drug Name:


Generic Name and Formulations:
Tetanus and reduced diphtheria toxoids, acellular pertussis vaccine; aluminum phosphate adsorbed; susp for IM inj; contains 2-phenoxyethanol and traces of formaldehyde, glutaraldehyde.

Sanofi Pasteur, Inc.

Therapeutic Use:

Indications for ADACEL:

Diphtheria, tetanus, and pertussis booster immunization in persons 10–64 years of age.

Adults and Children:

<10yrs or ≥65yrs: not recommended. 10–64yrs (≥5yrs after last dose of tetanus toxoid, diphtheria toxoid, and/or pertussis-containing vaccine): 0.5mL IM once into deltoid muscle.


Anaphylaxis associated with any previous diptheria, tetanus, pertussis vaccine. Encephalopathy within 7 days after previous pertussis-containing vaccine.


Progressive or unstable neurologic disorders. Guillain-Barre syndrome (within 6 weeks) of previous tetanus vaccination. Previous Arthus-type hypersensitivity reaction: not recommended until ≥10yrs after prior dose of tetanus toxoid-containing vaccine. Immunodeficiency. Risk of syncope. Have epinephrine inj (1:1000) available. Latex allergy (prefilled syringes). Pregnancy (Cat.C). Nursing mothers.


Concomitant vaccines: see full labeling. Immunosuppressants (eg, radiation, chemotherapy, high-dose steroids): may get suboptimal response.

Pharmacological Class:


Adverse Reactions:

Local reactions, headache, body ache or muscle weakness, tiredness, chills, fever, GI upset.


Register pregnant patients exposed to Adacel by calling (800) 822-2463.

How Supplied:

Single-dose vials—5, 10; Single-dose prefilled syringes—5

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