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ACTHIB
Vaccines
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Drug Name:

ACTHIB Rx

Generic Name and Formulations:
Haemophilus b conjugate 10mcg (tetanus toxoid conjugate) per 0.5mL; pwd for IM inj after reconstitution with saline, Sanofi Pasteur DTaP, Tripedia.

Company:
Sanofi Pasteur, Inc.

Therapeutic Use:

Indications for ACTHIB:

Combined with supplied saline diluent by reconstitution: for the active immunization of children 2–18 months of age against H. influenzae type b. Combined with Tripedia (DTaP) vaccine by reconstitution: for the active immunization of children 15–18 months of age against H. influenzae type b, diphtheria, tetanus, and pertussis.

Children:

Inject IM in thigh or deltoid. Reconstituted with DTaP, or saline: <2months: not recommended. As 1st, 2nd, 3rd dose in series: 0.5mL at 2, 4, and 6 months. Reconstituted with Tripedia (DTaP): <15months: not recommended. As 4th dose in series: 0.5mL at 15–18months, then 5th dose at 4–6yrs. Previously unvaccinated children: see literature.

Warnings/Precautions:

Immunodeficiency/ suppression, malignancies: may get suboptimal response. Delay administration in active infection or fever. Have epinephrine inj (1:1000) available. Protection begins 2 weeks after inoculation. Pregnancy (Cat.C): not recommended.

Pharmacological Class:

Hib (PRP-T).

Adverse Reactions:

Local pain, redness, swelling, irritability, drowsiness, anorexia, fever, GI upset.

Note:

ActHIB may be reconstituted with either supplied saline diluent or Sanofi Pasteur DTaP, Tripedia. TriHIBit is a product of the reconstitution of ActHIB with Tripedia for the 4th dose only.

How Supplied:

Single-dose vials—5 (w. saline diluent)
Single-dose vials—5 (w. 5 Tripedia vials as diluent)

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